Why the study?
Paraplegia is a devastating complication during extensive aortic arch repair, motivating a comparison between the frozen elephant trunk technique and the classical elephant trunk technique followed by second-stage TEVAR.
Does the frozen elephant trunk technique alone compared to the classical elephant trunk technique followed by second-stage TEVAR reduce paraplegia and improve outcomes in patients undergoing extensive aortic arch repair?
Does the frozen elephant trunk technique alone compared to the classical elephant trunk technique followed by second-stage TEVAR reduce paraplegia and improve outcomes in patients undergoing extensive aortic arch repair?
The classical elephant trunk technique followed by second-stage TEVAR may offer a lower risk of paraplegia compared to the frozen elephant trunk technique for extensive aortic arch repair, with comparable mid-term survival.
Hypothesis-generating for paraplegia risk with FET; should not yet change practice pending randomized data.
Paraplegia is one of the most devastating complications during extensive aortic arch repair. We retrospectively analyzed our results by comparing primary repair using the frozen elephant trunk technique (FET) and the classical elephant trunk technique (CET) followed by second-stage thoracic endovascular aortic repair (TEVAR), which has been performed since 2009. Between March 1997 and September 2015, 91 patients (the mean age: 70 ± 8.6 years old, 73 men and 18 women) underwent total aortic arch replacement with either the FET (54 cases) or CET (37 cases). The CET was followed by second-stage TEVAR with a median duration of 36 days. The number of in-hospital deaths was 2 (3.7%) in FET and none in CET. The overall survival was 73% in FET and 83% in CET at 5 years with no significant difference (p=0.73). Aortic events occurred in 12 cases (22%) in FET and 3 (8%) in CET. The rate of freedom from aortic events was 77% in FET and 91% in CET at 5 years with no significant difference (p=0.45). Five neurologic events (9%) occurred after the FET, and 3 events (8%) occurred after the CET (p=0.85). No patients in the CET group experienced paraplegia, while the FET group showed a relatively high paraplegia rate (17%, p=0.014).The FET with primary repair for extensive aortic arch repair had an acceptable hospital mortality rate and aortic events but was associated with a high incidence of paraplegia. The CET followed by second-stage TEVAR achieved better early results with a low risk of paraplegia and may produce a favorable mid-term surgical outcome for extensive aortic arch repair.
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A 2020 study studied this question.
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