BACKGROUND: Epikeratoplasty for keratoglobus performed to tectonically support the thin globular cornea may have complications such as interface opacities. METHODS: We report the case of a patient with persistent interface opacities and epithelial cysts following epikeratoplasty for keratoglobus that were treated primarily by washouts and repeated argon laser photocoagulation. RESULTS: Interface opacities led to massive epithelial inclusion cysts. Direct removal of these cysts and placement of a new lamellar graft resulted in a favorable outcome. CONCLUSION: Massive epithelial inclusion cysts may develop in the lamellar interface after epikeratoplasty. Direct surgical removal was successful.
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