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February 1, 2000AJP Heart and Circulatory Physiology

Frequency limits on aortic baroreceptor input to nucleus tractus solitarii

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Why the study?

Does the frequency and pattern of aortic depressor nerve stimuli affect NTS action potential responses and lumbar sympathetic nerve activity in urethan-anesthetized rats?

Population

Urethan-anesthetized rats

Design

Preclinical

Authors

ZLZhi LiuUniversity of Electro-CommunicationsCCChao-Yin ChenNational Taiwan University HospitalABAnn C. BonhamUniversity of Rochester

Discussion

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Implication

May limit baroreflex sympathoinhibition at high frequencies; hypothesis-generating for NTS processing in blood pressure regulation.

Structured PICO

Does the frequency and pattern of aortic depressor nerve stimuli affect NTS action potential responses and lumbar sympathetic nerve activity in urethan-anesthetized rats?

P
Population
Urethan-anesthetized rats
I
Intervention
100 aortic depressor nerve stimuli delivered in constant or phasic patterns (0.8-48 Hz)
O
Outcome
NTS action potential responses of neurons classified as second or higher order and averaged lumbar sympathetic nerve activity responsessurrogate

Frequency-dependent depression of baroreceptor signals at NTS synapses may limit baroreflex sympathoinhibition and affect blood pressure regulation.

Cite This Study

Liu et al. (2000) studied this question.

synapsesocial.com/papers/6a893156c9c00c271ba2b018https://doi.org/10.1152/ajpheart.2000.278.2.h577
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Baroreflex frequency-response characteristics to aortic depressor and carotid sinus nerve stimulation in rats1996 · 52 citations
  2. 2Synaptic mechanisms regulating cardiovascular afferent inputs to solitary tract nucleus1990 · 123 citations
  3. 3Frequency dependence of synaptic transmission in nucleus of the solitary tract in vitro1986 · 157 citations
  4. 4An intracellular study of time-dependent cardiovascular afferent interactions in nucleus tractus solitarius1988 · 88 citations
  5. 5Acute resetting in two functionally different types of carotid baroreceptors.1992 · 60 citations