The kinetics of formation of the Semliki Forest virus nucleocapsid were studied by following the incorporation of pulse-labeled capsid protein into the 140S particle. The process was rapid; within 5 min, the maximum level of label incorporation was reached. Using cycloheximide, the assembly was shown to be dependent on continuing protein synthesis. No pool of soluble capsid protein could bedetected.
No takes yet. Share an insight, caveat, or question.
Hans Söderlund (1973) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: