Abstract figure legend A, mice were generated which express the Ca2+ indicator GCamp6F and an inducible Cre-recombinase in exocrine acinar cells. B, expression of GCamp6F specifically in acinar cells was induced by tamoxifen treatment to activate the Cre-recombinase. C, following surgery to expose a portion of the pancreas, multiphoton imaging was performed to visualize Ca2+ signals in vivo. D, Ca2+ signals (kinetics from cells in the field of view, plus maximum projection images for the period of stimulation) in fasted animals, following feeding, by injection of the hormone cholecystokinin (CCK) and direct nervous stimulation.
No takes yet. Share an insight, caveat, or question.
Ekmark et al. (2003) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: