Tetracycline-ResistantVibrio choleraeO1, Kolkata, India

To the Editor: Cholera, caused by toxigenic strains of Vibrio cholerae O1 or O139, continues to be a major cause of illness and death, particularly in developing countries. Treatment consists of early administration of rehydration therapy with appropriate oral or intravenous fl uids. The World Health Organization recommends antimicrobial drug treatment for severely dehydrated patients with suspected cholera because it substantially shortens the duration of diarrhea by reducing the volume of watery stools, decreases fl uid requirements, and limits transmission by decreasing fecal excretion of V. cholerae (1). The progressive increase in resistance to multiple drugs among strains causing clinical cases of cholera in developing countries is becoming a serious concern. We report the emergence of tetracyclineresistant V. cholerae O1 in a welldefi ned population in Kolkata, India, during 2007-2009.