Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 14, 2024Thrombosis and HaemostasisOpen Access

Anticoagulant Therapy in Pregnant Women with Mechanical Heart Valves: Italian Federation of Centers for Diagnosis and Surveillance of the Antithrombotic Therapies (FCSA) Position Paper

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Anticoagulant management in pregnant women with mechanical heart valves is challenging, with unresolved issues regarding optimal agent selection, target anticoagulation levels, and balancing maternal thrombotic risk against fetal teratogenicity.

What is the optimal management of anticoagulant therapy in pregnant women with mechanical heart valves to balance maternal thrombotic risk and fetal teratogenicity?

Population

Pregnant women with mechanical heart valves

Design

Position paper and consensus document based on a comprehensive literature review

Authors

ECElena CampelloUniversity of PaduaPBPaolo BucciarelliVascular MedicineFCFilippo CatalaniUniversity of Padua

Discussion

Loading...

Member takes

Implication

Anticoagulation in pregnant women with MHVs remains high-risk; review leaves open optimal regimens balancing maternal and fetal outcomes.

Structured PICO

What is the optimal management of anticoagulant therapy in pregnant women with mechanical heart valves to balance maternal thrombotic risk and fetal teratogenicity?

P
Population
Pregnant women with mechanical heart valves (MHVs)
I
Intervention
Anticoagulant therapy management (including vitamin K antagonists and heparins)
O
Outcome
Maternal and fetal outcomes

This FCSA position paper provides expert consensus and practical guidance on balancing maternal thrombotic risks and fetal teratogenic risks when managing anticoagulation in pregnant women with mechanical heart valves.

Cite This Study

Campello et al. (2024) studied this question.

synapsesocial.com/papers/6a8951f5a4df84145ecb00aehttps://doi.org/10.1055/a-2325-5658

Topics

Anticoagulation in AF
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Outcome of pregnancy in women with valve prostheses.1994 · 307 citations
  2. 2Limited dose warfarin throughout pregnancy in patients with mechanical heart valve prosthesis: a meta-analysis2014 · 97 citations
  3. 3Anti-Xa based dose changes during low molecular weight heparin anticoagulation for mechanical prosthetic heart valves during pregnancy2018 · 6 citations
  4. 42018 ESC Guidelines for the management of cardiovascular diseases during pregnancy2018 · 2,324 citations
  5. 52021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation2021 · 1,130 citations