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The usefulness of sodium percarbonate, an inexpensive, safe and easily handled reagent for the transformation of nitriles into amides was investigated. Aromatic nitriles lacking ortho-substituents and heteroaromatic nitriles were efficiently transformed into amides; while ortho-substituted aromatic nitriles and aliphatic nitriles gave moderate yields of the corresponding amides.
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Kabalka et al. (1990) studied this question.
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