Case series reveals distinct lymphoscintigraphic patterns across lower extremity swelling disorders, highlighting the critical role of clinical context in nuclear imaging interpretation.
Lower extremity swelling has a broad differential diagnosis, including lymphedema, obesity-induced lymphedema, phlebolymphedema, and lipedema. Although these conditions may appear similar clinically, their pathophysiology and lymphoscintigraphic findings differ. Obesity, venous insufficiency, and abnormal adipose tissue can complicate image interpretation. We present four representative cases to illustrate characteristic imaging patterns across these conditions. These cases highlight the importance of interpreting lymphoscintigraphy in a clinical context.
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Oh et al. (2026) studied this question.
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