Why the study?
Cardiac involvement in systemic diseases is often silent or oligosymptomatic, warranting investigation of cardiac abnormalities to enable early diagnosis and treatment to reduce morbidity and mortality.
Are systemic illnesses (hematological, endocrinal, renal) associated with cardiac function abnormalities in children?
Are systemic illnesses (hematological, endocrinal, renal) associated with cardiac function abnormalities in children?
Systemic illnesses in children, such as hematological, endocrinal, and renal diseases, are associated with significant subclinical ECG and echocardiographic abnormalities.
Supports cardiac evaluation in children with systemic illnesses; leaves open whether abnormalities predict outcomes or warrant intervention.
Background:There are wide number of diseases of almost every system in the body which can affect heart in a number of different ways including increasing demands on the heart ,ventricular dysfunction ,rhythm abnormalities ,valve abnormalities ,pulmonary pressures and lot more.Cardiac involvement in systemic diseases is usually silent or oligosymptomatic and includes different pathophysiological mechanisms such as myocardial inflammation, infarction ,subendocardial vasculitis,valvular disease and different patterns of fibrosis. Objective : To study association between systemic illnesses (hematological, endocrinal , renal) and cardiac function abnormalities as ventricular function,cardiac dimensions ,pulmonary artery pressure and pericardial effusion,for early diagnosis and treatment to decrease morbidity and mortality in patient with systemic illness. Design/Method:It was a cross sectional,descriptive study The present study was conducted in the Department of Pediatrics, LLRM Medical College,Meerut,Uttar Pradesh over a period of 1 year (June 2019-June 2020) Results: Cardiac findings in all three groups show ECG abnormalities and echocardiographic changes compared to general population. ECG abnormalities were prolonged PR interval and sinus tachycardia while echocardiographic changes mainly left ventricular(LV) dilatation and hypertrophy ,increased cardiac output ,ventricular dysfunction and pulmonary arterial hypertension(PAH),were noted in a significant proportion of patients. Conclusion:Systemic illnesses affect cardiac parameters in various ways including prolonged PR interval,cardiac dilatation,chamber hypertrophy ,high cardiac output,high cardiac index ,PAH and ventricular dysfunction.
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Tomar et al. (2021) studied this question.
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