Neutropenic Ulceration

Neutropenic ulceration is a distinctive clinical entity observed in severely myelosuppressed patients, such as those with acute leukemia. This case report demonstrates that evidence of its initial resolution may indicate the earliest stages of bone marrow recovery before this is reflected in the peripheral circulation through the return of functioning neutrophils. The possible influences of leukemic infiltration and bacterial superinfection in its initiation and progression are discussed.