Key result
Early pericardiocentesis and anti-tuberculous therapy fully resolves effusion in tuberculous pericarditis.
Why the study?
Tuberculous pericarditis is a rare, life-threatening manifestation of extrapulmonary tuberculosis that remains a significant diagnostic challenge due to its nonspecific presentation and overlap with other etiologies.
Case Report (n=1)
Answers are grounded in this paper and cite their sources.
This case highlights the importance of early multimodal imaging and pericardiocentesis in diagnosing and managing tuberculous pericarditis presenting with early tamponade in migrants from endemic regions.
Tuberculous pericarditis (TBP) is a rare but potentially life-threatening manifestation of extrapulmonary tuberculosis, particularly in regions with low tuberculosis (TB) prevalence. It accounts for a small fraction of pericardial effusion cases in high-income countries, yet remains a significant diagnostic challenge due to its nonspecific presentation and overlap with other infectious, inflammatory, or malignant causes. Here, we present a case of a tuberculous pericarditis in a 32-year-old male, originally from Congo, who presented with constitutional symptoms, pleuritic chest pain, and tachycardia shortly after migrating to the United Kingdom from South Africa. Initial investigations revealed a large pericardial effusion with early signs of tamponade, prompting urgent pericardiocentesis and further imaging. This case reinforces the need for timely recognition, multidisciplinary management, and public health awareness to mitigate the morbidity associated with tuberculous pericarditis.
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Shayo et al. (2025) conducted a case report in Tuberculous pericarditis (n=1). Pericardiocentesis and anti-tuberculous therapy was evaluated. Early pericardiocentesis and anti-tuberculous therapy led to complete resolution of the pericardial effusion in a 32-year-old male migrant with tuberculous pericarditis.
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