Xga linkage data on a large family with Reifenstein's syndrome is reported. The pedigree was analyzed directly and the data were combined with that from the other linkage study in the literature to allow a numerical estimate of the likelihood of the recombination fraction, based on all the linkage data available. It was concluded that there is not close linkage between Xga and Reifenstein's syndrome. A suggestion was, however, found of tight linkage between the genes for color blindness and Reifenstein's syndrome, but this result was not definite because of the small amount of data available.
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Bremner et al. (1974) studied this question.
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