Key result
Pre-discharge exercise capacity was a strong predictor of reduced death and re-infarction (RR 0.82; 95% CI 0.72-0.93; P<0.001) following STEMI, irrespective of reperfusion strategy.
Why the study?
Does pre-discharge exercise testing provide prognostic information for death and re-infarction in STEMI patients treated with primary PCI or fibrinolysis?
Population
1,164 patients with ST-elevation acute myocardial infarction discharged alive who performed a pre-discharge…
Design
Cohort, Patients were originally randomized to primary PCI or fibrinolysis in…
Authors
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May aid post-STEMI risk stratification; leaves open whether testing alters management or outcomes in prospective trials.
Cohort (n=1,164)
Randomized to primary angioplasty (PCI) or fibrinolysis in the parent trial
Does pre-discharge exercise testing provide prognostic information for death and re-infarction in STEMI patients treated with primary PCI or fibrinolysis?
Relative Risk: 0.82 (95% CI 0.72–0.93)
p-value: p=<0.001
Pre-discharge exercise capacity remains a strong prognostic predictor of death and re-infarction in STEMI patients regardless of reperfusion strategy, while ST-depression is more predictive in those treated with fibrinolysis.
Nana Valeur (2004) conducted a cohort in ST-elevation acute myocardial infarction (STEMI) (n=1,164). Exercise capacity (assessed via pre-discharge exercise testing) was evaluated on Composite of death and re-infarction (RR 0.82, 95% CI 0.72-0.93, p=<0.001). Pre-discharge exercise capacity was a strong predictor of reduced death and re-infarction (RR 0.82; 95% CI 0.72-0.93; P<0.001) following STEMI, irrespective of reperfusion strategy.
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