Key result
The mid-cycle phase of the menstrual cycle was associated with a significant decrease in reflection index, stiffness index, and pulse wave velocity (p<0.05).
Why the study?
Does the mid-cycle phase of the menstrual cycle reduce arterial stiffness indices in healthy young women?
Observational
Does the mid-cycle phase of the menstrual cycle reduce arterial stiffness indices in healthy young women?
Arterial stiffness indices decrease significantly during the mid-cycle of the menstrual cycle in healthy young women, suggesting a potential vascular protective effect of estrogen.
Arterial stiffness indices decrease mid-cycle in young women; hypothesis-generating for estrogen effects, should not change practice.
INTRODUCTION: Arterial compliance will result in stabilizing the fluctuations in arterial pressure and blood flow. So arterial stiffness can be a good indicator for monitoring the cardiovascular system. Arterial stiffness can be measured using indices like reflection index (RI), stiffness index (SI) and Brachial Finger Pulse Wave Velocity (BFPWV). OBJECTIVES: Aim of our study was to evaluate the changes in RI, SI and BFPWV during different phases of the menstrual cycle and to correlate RI with SI in healthy female subjects between the age group of 18-30 years from Bangalore, India. MATERIALS AND METHODS: Basal recordings of RI and SI were determined by Photo Pulse Plethysmography (PPG) picked up from the fingertip using BIOPAC system and BFPWV was obtained using Doppler. Recordings were obtained at three different time points during the menstrual cycle. Analysis was done using repeated measures ANOVA with Bonferroni correction. RESULT: There was a significant decrease in above parameters p <0.05 during the mid-cycle. Correlation between RI and SI was also significant p<0.05. CONCLUSION: These findings suggests that the menstrual cycle affects the arterial stiffness and one of the factor is oestrogen. Hence, women are less prone to the incidence of cardiovascular diseases before menopause. Screening for arterial stiffness in a general population, using these indices is valid, economical and reliable.
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M Madhura (2014) conducted an observational in Healthy. Menstrual cycle phases vs. Different phases of the menstrual cycle was evaluated on Reflection index (RI), stiffness index (SI) and Brachial Finger Pulse Wave Velocity (BFPWV) (p=<0.05). The mid-cycle phase of the menstrual cycle was associated with a significant decrease in reflection index, stiffness index, and pulse wave velocity (p<0.05).
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