In vitro study uncovers species-specific antifungal resistance among clinical Fusarium isolates, highlighting distinct therapeutic vulnerabilities in deep versus superficial infections.
Fusarium isolates from 75 Italian patients were identified by molecular methods, and their susceptibilities to antifungals were tested in vitro. Fusarium verticillioides was the species most frequently isolated from deep-seated infections, and F. solani was the species most frequently isolated from superficial infections. F. solani isolates showed high azole MICs, while F. verticillioides isolates showed low posaconazole MICs.
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Tortorano et al. (2008) studied this question.
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