Case Reports1 January 1958LONG CONTINUING JAUNDICE FOLLOWING MINIMAL CHLORPROMAZINE (THORAZINE) MEDICATIONHERMAN M. MEYER, M.D., JEROME E. COOK, M.D., F.A.C.P.HERMAN M. MEYER, M.D.Search for more papers by this author, JEROME E. COOK, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-1-199 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMany reports have appeared regarding the occasional occurrence of jaundice in patients who are receiving or have recently received chlorpromazine. It is rather generally stated that the incidence of such jaundice is very low, around 1% or less, although some clinicians have had a less favorable experience, such as the three cases of jaundice in 26 patients reported by Isaacs, Macarthur and Taylor.1Our own experience, though meager, has been of a similarly frequent incidence of jaundice. The severity of the case here reported has given us caution in any free employment of the drug. While the conclusions voiced as...Bibliography1. IsaacsMacarthurTaylor BJGRM: Jaundice in relation to chlorpromazine therapy, Brit. M. J. 2: 1122-1124 (Nov. 5) 1955. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: St. Louis, Missouri*Received for publication July 23, 1956.From the Medical Service of the Jewish Hospital of St. Louis.Requests for reprints should be addressed to Jerome E. Cook, M.D., 4409 West Pine Boulevard, St. Louis 8, Missouri. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byExaggerated cholestasis and hepatic fibrosis following simultaneous administration of chlorpromazine and sodium valproatePsychological Consequences of Drug JaundiceInterpretation of the Liver BiopsyPhenothiazine und Azaphenothiazine als HeilmittelXanthomatous biliary cirrhosis following chlorpromazineChronic chlorpromazine jaundicePROBABLE HEPATIC ALLERGY TO CHLORPROMAZINE AND DELIBERATE DESENSITIZATION*LEO WAITZKIN, M.D.DRUG-INDUCED HEPATIC INJURY*HANS POPPER, M.D., F.A.C.P., FENTON SCHAFFNER, M.D., F.A.C.P.Tranquilizers in Surgery 1 January 1958Volume 48, Issue 1Page: 199-202KeywordsBileChlorpromazineDrugsMedical services ePublished: 1 December 2008 Issue Published: 1 January 1958 PDF downloadLoading ...
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MEYER et al. (1958) studied this question.