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June 1, 2002Antimicrobial Agents and ChemotherapyOpen Access

Amphotericin B Formulations Exert Additive Antifungal Activity in Combination with Pulmonary Alveolar Macrophages and Polymorphonuclear Leukocytes against Aspergillus fumigatus

Emmanuel Roilides Caron A. Lyman Joanna Filioti Onome Akpogheneta Tin Sein C. G. Lamaignere Rūta Petraitienė Thomas J. Walsh

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Abstract

Deoxycholate amphotericin B (DAMB) and amphotericin B lipid complex (ABLC) additively augmented the fungicidal activity of pulmonary alveolar macrophages against the conidia of Aspergillus fumigatus. DAMB, ABLC, and liposomal amphotericin B similarly displayed additive effects with polymorphonuclear leukocytes in damaging the hyphal elements of A. fumigatus.

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Roilides et al. (2002) studied this question.

synapsesocial.com/papers/6a896e8cd76717fba3eb1fc1 https://doi.org/10.1128/aac.46.6.1974-1976.2002

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Damage to Pseudohyphal Forms of Candida albicans by Neutrophils in the Absence of Serum In VitroIn Vitro Study · 1978 · 189 citations
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