Plakoside A ( 1a ) and B ( 2a ), two unique glycosphingolipids belonging to a new class of prenylated glycolipid, have been isolated from the marine sponge Plakortis simplex, and their structures have been determined by spectroscopic and chemical means. Plakosides are strongly immunosuppressive on activated T cells and proved to be useful natural models for an improved comprehension of the structural requirements for immunomodulating activity of glycosphingolipids.
No takes yet. Share an insight, caveat, or question.
Costantino et al. (1997) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: