Answers are grounded in this paper and cite their sources.
Directly linked 1,3-azoles are found as substructures in important naturally occurring products that have interesting biological activities as well as fascinating structures. Therefore, many research groups are working on their total syntheses. Although new approaches have been developed to prepare these targets, classical 1,3-azole formation methodologies are still being used for this purpose. This report provides an overview of polyazole-containing natural products and the different strategies for the synthesis of directly linked 1,3-azole moieties.
No takes yet. Share an insight, caveat, or question.
Riego et al. (2005) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: