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Case report demonstrates severe multisystem complications in recurrent retroperitoneal paraganglioma, highlighting the necessity of early diagnosis and ongoing monitoring.
Pheochromocytoma (PCС) and paraganglioma (PG) are malignant neuroendocrine tumors (NEO) of paraganglionic origin, producing biologically active substances and characterized by a variable clinical course. Currently, the main method of treatment of PCС and PG is radical surgical treatment; nevertheless, there is a life-long risk of tumor recurrence as well as distant metastases. Here we present a clinical case of recurrent retroperitoneal PG incidentally detected during hospitalization for decompensated diabetes mellitus (DM). In the case PG caused acute cerebral circulatory failure, arterial hypertension, DM, heart rhythm disorders, potentially preventable with timely diagnosis of the disease. The peculiarity of the detected PG was its recurrent course despite repeated surgical interventions.
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Маркова et al. (2025) studied this question.
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