Key result
COVID-19 restriction measures and reduced access to routine INR monitoring were associated with a dramatic increase in stuck mechanical valves, leading to urgent surgeries and a 40% mortality rate.
Why the study?
COVID-19 restriction measures made regular INR assessment challenging for mechanical valve replacement patients, raising concerns about risks of stuck valve complications from ineffective anticoagulation.
Case Report (n=10)
No
COVID-19 restriction measures severely impacted routine INR monitoring, leading to a dramatic and life-threatening increase in stuck mechanical valves among patients on chronic warfarin therapy.
May warrant alternative INR monitoring during restrictions; hypothesis-generating for resilient anticoagulation strategies in mechanical valve patients.
Stuck valve is a very rare and severe complication that occurs in mechanical valve replacement patients with ineffective anticoagulation. However, with COVID-19 restriction measures, it became challenging to regularly assess INR to make sure it falls within the target therapeutic range to prevent this complication. We present a series of 10 patients who either underwent transthoracic echocardiography for a suspected stuck valve or were seen at the outpatient valve clinic with the residual consequences of a stuck valve during the COVID-19 restriction measures in our institute. Stuck prosthetic valves incident has increased significantly during this period, particularly those in the mitral position for which urgent replacement and prolonged hospitalization were necessary. Particularly with the COVID-19 restrictions in place, these cases highlight the need for physicians to be aware of the dramatic increase in the incidence of stuck prosthetic valves in patients on chronic warfarin therapy.
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Vriz et al. (2021) conducted a case report in Stuck mechanical valve (n=10). COVID-19 restriction measures (reduced access to INR monitoring) vs. Pre-pandemic period (historical) was evaluated on Incidence and clinical outcomes of stuck mechanical valves. COVID-19 restriction measures and reduced access to routine INR monitoring were associated with a dramatic increase in stuck mechanical valves, leading to urgent surgeries and a 40% mortality rate.
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