Key result
Non-rheumatic valvular heart disease was associated with a significantly higher prevalence of coronary artery disease compared to rheumatic valvular heart disease (44.44% vs 9.26%, p<0.001).
Cross-Sectional (n=126)
Yes
Absolute Event Rate: 44.44% vs 9.26%
p-value: p=<0.001
Significant coronary artery disease is highly prevalent (14.28%) in Indian patients undergoing valvular heart surgery, particularly in those with non-rheumatic etiologies (44.44%).
Non-rheumatic VHD may warrant heightened preoperative CAD screening; cross-sectional data leaves open etiology-specific mechanisms.
Heart disease is a growing problem, particularly in developing countries. India has quoted to have 12.2% and 12% prevalence of coronary artery disease and rheumatic valvular heart disease respectively. Some older reports suggest that rheumatic fever, i n addition to producing specific injuries to small coronary arterial branches may accelerate the development of coronary atherosclerosis.
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Hiranya Kumar Saharia (2016) conducted a cross-sectional in Valvular heart disease (n=126). Non-rheumatic valvular heart disease vs. Rheumatic valvular heart disease was evaluated on Prevalence of significant coronary artery disease (p=<0.001). Non-rheumatic valvular heart disease was associated with a significantly higher prevalence of coronary artery disease compared to rheumatic valvular heart disease (44.44% vs 9.26%, p<0.001).
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