In a preliminary report on this subject, 1 I presented a number of cases to show that, a hypercholesterinemia is usually to be found in cases of chronic nephritis which are progressing favorably, and that a normal or subnormal figure for the serum cholesterol, in cases of chronic nephritis, is of distinct prognostic importance and value. The measure of cholesterinemia in the cases enumerated in my early paper accurately foretold the prognosis in individual cases. The study of the chemistry of the blood has made giant strides during the past few years, and we are now enabled to measure accurately, especially the nonnitrogenous constituents of the blood — total nonprotein nitrogen, urea nitrogen, creatinin, uric acid and sugar. There seems to be little disagreement as to the best quantitative methods to employ, and the clinician has a right to accept the quantitative determination without a doubt. Much work along this line
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Edwin Henes (1920) studied this question.