Zeger and Liang (1986, Biometrics 42, 121-130) proposed a procedure for analyzing nonnormal longitudinal data in the context of the generalized linear model. This procedure is extended to model variance heterogeneity, allowing the observations to come from distributions with different scale parameters. Loss of efficiency is evaluated when heterogeneity of scale factor is ignored.
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Myunghee Cho Paik (1992) studied this question.
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