Article1 May 1959CHEMOTHERAPY OF MALIGNANT TUMORSL. F. LARIONOVL. F. LARIONOVSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-5-1122 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt(Corresponding member of the Academy of Medical Sciences of the U.S.S.R.)A development of the problem of the drug therapy of cancer is possible along two main roads. The first is the development of methods for the medicinal stimulation of the protective forces of the organism in relation to the developing tumor, for the purpose of obtaining a regression of the process or, at least, the cessation of its further spread. The second is the search for medicinal preparations which can bring about the death of the tumor by means of direct interference with the metabolism of the malignant tissue...Bibliography1. 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Reactions of mice with primary subcutaneous tumors to injection of a hemorrhage-producing bacterial polysaccharide, J. Nat. Cancer Inst. 4: 461, 1944. Google Scholar43. Schulte G: Experiences with new cytostatic therapy in blood dyscrasias and carcinomata; differentiation of their effects from the effects of X-rays, Ztschr. f. Krebsforsch. 58: 500, 1952. CrossrefGoogle Scholar44. UmezawaTakeuchiNittaOkamiYamamotoYamaoka HTKYTS: Studies on anti-tumor substances produced by microorganisms. III. On sarkomycin produced by a strain resembling Streptomyces erythrochromogenes , J. Antibiotics, Ser. A., Tokyo 6: 147, 1953. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: MOSCOW, U.S.S.R.*Received for publication August 4, 1958.Translated from the Russian by Medical Documentation Service, Philadelphia, Pennsylvania.†Patol. Fiziol. i Eksper. Terap. 1 (3): 14-21, 1957.Requests for reprints should be addressed to Mr. Scott Adams, Librarian, National Institutes of Health, Bethesda 14, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChemotherapy of Cancer 1 May 1959Volume 50, Issue 5Page: 1122-1134KeywordsBiologicsChemotherapyDrug therapyFolic acidHormonal therapyMalignant tumorsNucleic acidsProteinsSarcoma ePublished: 1 December 2008 Issue Published: 1 May 1959 PDF downloadLoading ...
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