Stereospecific Synthesis ofN-(Diphenylmethylene)-α,β-didehydroamino Acid Methyl Esters from β-Hydroxy-α-amino Acids

All articles of this category N -(Diphenylmethylene)-α,β-didehydroamino acid methyl esters 2b-d are prepared with absolute geometric selectivity from inexpensive β-hydroxyamino acids through the intermediates N -(diphenylmethylene)- β-hydroxyamino acid methyl esters 1b-d . Besides, an easy conversion from E isomers to the corresponding Z isomers was performed, thus avoiding the use of the uncommon allo -β-hydroxyamino acids as starting materials.