The replication of the ring-shaped polyoma DNA has been investigated. The replicative intermediate has been identified and characterized; it consists of molecules containing both circular and nicked strands, not longer than the strands of the DNA found in viral particles. The findings exclude certain proposed methods of replication of ring-shaped DNA and are compatible with Cairns' model.
No takes yet. Share an insight, caveat, or question.
Bourgaux et al. (1969) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: