Multicenter observational study to evaluate epidemiology and resistance patterns of common intensive care unit-infections

BACKGROUND: There is limited data regarding the microbiology of Intensive Care Unit (ICU)-acquired infections, such as ventilator-associated pneumonia (VAP), catheter-associated urinary tract infections (CAUTI), and catheter-related bloodstream infections (CRBSI) from India. OBJECTIVES: To explore the microbiology and resistance patterns of ICU-acquired infections and evaluate their outcomes. MATERIALS AND METHODS: This was a multicenter observational study, conducted by Indian Society of Critical Care Medicine (MOSER study) between August 2011 and October 2012. Patients in the ICU ≥48 h with any ICU-acquired infection within 14 days of index ICU stay were included. Patient demographics, relevant clinical, and microbiological details were collected. Follow-up until hospital discharge or death was done, and 6-month survival data were collected. RESULTS: constituted only 2.4% of isolates. Mortality rates were 26%, 11.9%, and 34.6% in VAP, CAUTI, and CRBSI, respectively. CONCLUSION: is uncommon in the Indian setting.