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Clear cell chondrosarcoma (CCCS) is a very rare malignant bone tumor that can behave clinically as a benign or low-grade malignant bone tumor. It was first reported as a clear cell variant of chondrosarcoma by Unni et al. in 1976. 1) CCCS has a strong predilection for the epiphysis or metaphysis of long bones, especially the proximal end of the femur and humerus. However, there are only three cases of CCCS in the diaphysis of long bones 2,3) and furthermore, this tumor has never been reported to affect the diaphysis of the tibia.
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Kang et al. (2014) studied this question.
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