Population
HEK293 cells and polarized medullary-thick ascending limb cells expressing MaxiK channel isoforms rbslo1 and…
Design
Preclinical
Authors
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Identifies a key determinant of MaxiK trafficking in renal cells; leaves open its impact on tubular function or cardiovascular homeostasis in vivo.
The cytoplasmic tail of the rbslo1 isoform of the MaxiK channel is essential for its proper trafficking and expression at the cell surface.
Wang et al. (2003) studied this question.
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