Answers are grounded in this paper and cite their sources.
Metal ions are important for many biological processes and are steadily available in the human body. Metal concentrations can be extremely high in diseased areas of various pathological conditions. Some synthetic and natural drugs need to be activated by metal ions as prodrugs. In this review, we provide a few examples to illustrate how metal ions activate and mediate drug targeting in the body. This knowledge may be helpful for the development of more effective drugs and pharmaceutical formulations.
No takes yet. Share an insight, caveat, or question.
Tang et al. (2012) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: