Review uncovers molecular pathways underlying exercise-enhanced insulin sensitivity in type 2 diabetes, highlighting the utility of omics for personalized training strategies.
• Exercise impacts skeletal muscle and systemic metabolism, yet understanding the complex molecular mechanisms behind these effects remains a key research challenge. • Mapping the molecular effects of exercise with advanced “omics” can advance our understanding of muscle function and metabolism. • Exercise holds promise for managing and preventing type 2 diabetes, emphasizing the need for more research on individualized training and its molecular effects.
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Zierath et al. (2024) studied this question.
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