Key result
Age, surgical invasiveness, history of renal disease or anemia, and abnormal ECG were significant predictors of perioperative complications, which occurred in 6.3% of patients overall.
Why the study?
Do abnormal pre-operative tests and medical history predict perioperative complications in patients undergoing elective surgery?
Cohort (n=1,363)
No
Do abnormal pre-operative tests and medical history predict perioperative complications in patients undergoing elective surgery?
Age, surgical invasiveness, medical history, and abnormal ECG are better predictors of perioperative complications than routine laboratory tests, supporting a targeted rather than routine approach to pre-operative testing.
Supports selective preoperative testing over routine labs; hypothesis-generating pending prospective validation.
BACKGROUND: Laboratory tests, electrocardiogram (ECG) and chest X-rays still serve as part of the routine assessment before elective surgery in many institutions, even though there is little evidence of their predictive value relating to perioperative complications. This study investigates the correlation of abnormal findings in pre-operative tests and pathologic findings in the medical history with perioperative complications. METHODS: Patients scheduled for elective surgery in a secondary care hospital were included in this prospective cohort study. Abnormal pre-operative tests, significant findings from the medical history and perioperative complications were recorded. Regression analysis was performed in order to identify the strongest predictors for perioperative complications. RESULTS: A total of 1363 (56.1% female) patients were consecutively included in this study. The percentage of abnormalities in pre-operative tests ranged from 1.6% (electrolytes) and 29.7% (echocardiography). Eighty-six (6.3%) patients had at least one perioperative complication. The most frequent complications were hypo- or hypertension in 55 cases (4.0%), followed by 20 patients (1.5%) who suffered from hemodynamically relevant cardiac dysrhythmias such as supraventricular tachycardia, ventricular tachycardia, bradycardia and ventricular extrasystoles. The binary logistic regression analysis to identify predictors of perioperative complications showed significant results for age, invasiveness of the procedure, history of renal disease or anemia and abnormal ECG. CONCLUSION: Our results indicate that age, type of surgery and medical history are appropriate predictors of perioperative complications, whereas abnormalities in laboratory tests seem to have restricted ability in predicting adverse perioperative outcome.
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Fritsch et al. (2011) conducted a cohort in Elective surgery (n=1,363). Abnormal pre-operative tests and pathologic findings in medical history vs. Normal pre-operative tests and medical history was evaluated on Perioperative complications. Age, surgical invasiveness, history of renal disease or anemia, and abnormal ECG were significant predictors of perioperative complications, which occurred in 6.3% of patients overall.
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