Sequence Types and Antimicrobial Susceptibility of Invasive Streptococcus Pneumoniae Isolates From a Region With High Antibiotic Selective Pressure and Suboptimal Vaccine Coverage

Multilocus sequence typing was carried out on 95 invasive pneumococcal isolates belonging to the most common 7 serotypes currently circulating in Taiwan. The study confirmed continued prevalence in Taiwan of a few global clones and sequence types (STs) since the mid-1990s and identified the recent emergence of ST320 (19A) and ST902 (6A). Antimicrobial nonsusceptibility was common in the predominant STs of serotypes 14, 19A, 19F, and 23F.