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August 2, 2017The Journal of Experimental Medicine

Co-stimulatory function in primary germinal center responses: CD40 and B7 are required on distinct antigen-presenting cells

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Authors

MWMasashi WatanabeNational Cancer InstituteCFChiharu FujiharaOsaka Gakuin UniversityARAndrea J. RadtkeNational Institutes of Health

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Watanabe et al. (2017) studied this question.

synapsesocial.com/papers/6a8996505c716ca1a5d44ca2https://doi.org/10.1084/jem.20161955
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1CD40/CD154 Interactions at the Interface of Tolerance and Immunity2004 · 692 citations
  2. 2CD28 is required for germinal center formation1996 · 251 citations
  3. 3Mouse Inducible Costimulatory Molecule (ICOS) Expression Is Enhanced by CD28 Costimulation and Regulates Differentiation of CD4+ T Cells2000 · 441 citations
  4. 4Activation of thymic B cells by signals of CD40 molecules plus interleukin‐101995 · 38 citations