Usefulness of Telemetric Blood Pressure Monitoring in Hypertensive Patients with Chronic Kidney Diseases

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Hypertension with Chronic Kidney Disease (n=27). Intervention: Telemonitoring System (TMS) and lercanidipine vs. Baseline (pre-intervention). Primary outcome: Change in office systolic blood pressure (MD -10 mmHg, p=0.028).

M. Burnier

doi:10.4172/2161-0959.1000122

January 1, 2012Journal of Nephrology & TherapeuticsOpen Access

Usefulness of Telemetric Blood Pressure Monitoring in Hypertensive Patients with Chronic Kidney Diseases

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Why the study?

Does a telemonitoring system combined with lercanidipine improve blood pressure control in hypertensive patients with chronic kidney disease?

Key Points

To evaluate the potential clinical benefits of implementing a telemonitoring system alongside treatment adjustments in hypertensive patients with chronic kidney disease who experience uncontrolled blood pressure or adverse drug reactions.
Conducted as a pilot study embedded in ambulant routine clinical care.
Implemented a telemonitoring system concurrently with anticipated modifications to antihypertensive therapy in patients with uncontrolled hypertension or treatment-related side effects.
The abstract establishes the study rationale and implementation framework without reporting specific quantitative endpoint data or comparative effect sizes.
Intervention design targeted the dual challenges of inadequate blood pressure control and poor drug tolerance to potentially slow chronic renal disease progression.

Study Design

Type

Observational (n=27)

Multicenter

Yes

Structured PICO

Does a telemonitoring system combined with lercanidipine improve blood pressure control in hypertensive patients with chronic kidney disease?

P

Population

27 hypertensive patients with chronic kidney disease stage III-IV and uncontrolled blood pressure, followed for 4 months.

I

Intervention

Telemonitoring System (TMS) for home blood pressure, heart rate, and body weight monitoring, combined with the introduction and titration of lercanidipine (10-20 mg) for uncontrolled blood pressure.

O

Outcome

Change in office and home systolic and diastolic blood pressure at the end of the maintenance phase.surrogate

Main Result

Mean Difference: -10

p-value: p=0.028

Limitations

Observational design without a control group
Small sample size
Cannot disentangle the respective role of the telemonitoring system and the administration of lercanidipine because both interventions were simultaneous
Study design does not enable disentangling the respective roles of the telemonitoring system and the administration of lercanidipine because both interventions were simultaneous
Not a randomized controlled study

Implication

The combined use of home telemetric blood pressure monitoring and lercanidipine significantly improved blood pressure control in patients with chronic kidney disease.

Abstract

The quality of Blood Pressure (BP) control remains poor among patients with Chronic Kidney Diseases (CKD). It is therefore crucial to develop therapeutic strategies enabling improvement in BP control in order to retard the progression of the underlying renal diseases. The cornerstones of therapy include the use of effective and well tolerated drugs and a good drug adherence. In this pilot study conducted in ambulant routine care we evaluated the potential clinical benefits of implementing a Telemonitoring System (TMS) in parallel to an anticipated change of treatment in hypertensive CKD patients with uncontrolled hypertension and/or adverse reactions due to the current antihypertensive treatment.

Discussion

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Cite This Study

M. Burnier (2012) conducted an observational in Hypertension with Chronic Kidney Disease (n=27). Telemonitoring System (TMS) and lercanidipine vs. Baseline (pre-intervention) was evaluated on Change in office systolic blood pressure (MD -10 mmHg, p=0.028).

synapsesocial.com/papers/6a8998054de818ad79d442e8 https://doi.org/10.4172/2161-0959.1000122

View Full Paper

Ask AI

Bookmark

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Usefulness of Telemetric Blood Pressure Monitoring in Hypertensive Patients with Chronic Kidney Diseases

Key Points

Study Design

Structured PICO

Main Result

Limitations

Implication

Abstract

Discussion

Cite This Study

Usefulness of Telemetric Blood Pressure Monitoring in Hypertensive Patients with Chronic Kidney Diseases

Key Points

Study Design

Structured PICO

Main Result

Limitations

Implication

Abstract

Discussion

Cite This Study

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