Why the study?
Does prolonged intracoronary infusion of streptokinase improve lysis of extensive thrombus in a native coronary artery?
Does prolonged intracoronary infusion of streptokinase improve lysis of extensive thrombus in a native coronary artery?
Prolonged intracoronary infusion of streptokinase successfully lysed an extensive thrombus in a native coronary artery, facilitating subsequent angioplasty.
Should not alter practice; leaves open whether prolonged intracoronary streptokinase reliably lyses extensive coronary thrombi.
Several reports suggest that pretreatment of intracoronary thrombus with fibrinolytic agents may reduce the risk for complications during subsequent balloon angioplasty. We report a case, for the first time, of successful lysis of an extensive thrombus in a native coronary artery by administering a prolonged intracoronary infusion of streptokinase to facilitate subsequent angioplasty and discuss the management strategy when intracoronary thrombus is encountered.
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Kjellgren et al. (1994) studied this question.
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