The effect of various polyacids on the absorption spectrum of 7-methylamino-3-dimethylimino-3H-phenothiazine chloride (trimethylthionine chloride, Azure B) (1) was studied. The following polymers were used: poly(acrylic acid), several acrylic acid-acrylamide and acrylic acid-styrene copolymers, and three maleic acid-acrylamide copolymers. The spectroscopic measurements of the dye-polymer interactions showed that the dye molecules are associated with the polymer chain and that this association is strongly dependent on the copolymer composition, the distance between the carboxylic groups in the chain, and the internal structure of the macromolecule. At identical acrylic acid content of poly(styrene-co-acrylic acid), the triads sequence distributions affect also the intensity of the metachromatic band, though this influence is only of secondary importance compared to the other structural characteristics of the copolymers.
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Simionescu et al. (1975) studied this question.
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