A Pneumatically Actuated Target Stabilization Device for MRI-Guided Breast Biopsy

This paper introduces a novel tissue stabilization device for magnetic resonance imaging (MRI)-guided breast biopsy. The device is comprised of two pneumatically actuated support plates that would stabilize the biopsy target movements during needle insertion. An optimized geometry for the support plates allows for a good degree of tissue stabilization without relying on large compression forces. The plate configuration can also be adjusted inside the magnet bore using pneumatic actuators driven by pressure-controlled valves that are placed in the MRI control room. This capability allows for the compensation of the target displacement based on MRI image feedback. When combined with a separate needle drive mechanism, this stabilization device would enable in-bore MRI-guided breast biopsy. Experiments performed on chicken breast tissue with a prototype of the device demonstrate the effectiveness of this mechanism in increasing needle targeting accuracy using two simple error correction strategies. Furthermore, MRI compatibility tests are carried out to assess the performance of the device inside MRI.