Around us, we have many chiral macromolecules such as protein, carbohydrate, nucleic acid, steroids, peptides and phospholipids. Hence, these compounds exist in enantiomeric forms and we know that only one of the enantiomeric forms is important to us and another may or may not be useful. Therefore, chiral analysis of macromolecules has taken a unique place in analytical chemistry. The chiral separation of such macromolecules by analytical techniques is very difficult so only few papers were found in the literature, which has been discussed in this chapter. The presented chapter describes chiral analysis of macromolecule only by two analytical techniques i.e. high performance liquid chromatography and capillary electrophoresis. Besides, the efforts were made to discuss the future perspective regarding enantio-separation of such chiral macromolecules.
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Ali et al. (2018) studied this question.
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