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The vast range of reactions mediated by titanocene monochloride (Cp2TiCl, the Nugent reagent) in organic synthetic chemistry is reviewed. The power of the Nugent reagent in organic chemistry is demonstrated by its ability to promote and/or catalyse several efficient transformations under mild reaction conditions in the presence of several functional groups, in an environmentally friendly manner and with use of simple experimental procedures.
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Rosales et al. (2015) studied this question.
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