The vitamin E model compound, 2,2,5,7,8-pentamethyl-6-chromanol, has been oxidized with t-butyl hydroperoxide in chloroform in order to simulate in vivo oxidations due to lipid hydroperoxides. In the presence of a variety of alcohols, ranging from methanol to cholesterol, the corresponding 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanols were formed in fair to good yield and were the major products in each reaction.
No takes yet. Share an insight, caveat, or question.
Suarna et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: