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Retroviruses are a family of animal viruses with an RNA genome which replicate through a DNA intermediate. These viruses are widely distributed in vertebrates, and some have been found to be associated with neoplasia. In addition, some retroviruses, the so-called endogenous viruses, are also transmitted vertically integrated with germ-line chromosomal DNA.
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Shimotohno et al. (1981) studied this question.
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