Metal-Core−Organic Shell Dendrimers as Unimolecular Micelles

The synthesis and characterization of nanoparticle-cored dendrimers (NCDs), consisting of a metal core capped by arylpolyethers terminated with ester or carboxylate groups, are reported. These NCDs, comprising nanometer-sized gold clusters at the core and organic dendrons radially connected to the gold core by gold-sulfur bonds, were analyzed by TEM, TGA, UV, IR, and NMR spectroscopies. The density of the branching units connected to the core decreased from 1.90/nm(2) for a first-generation NCD (Au-G1(CO(2)Me)) to 0.80/nm(2) for a fourth-generation NCD (Au-G4(CO(2)Me)). Although the ester-terminated NCDs were stable and resisted aggregation, they were easily hydrolyzed to the corresponding water-soluble sodium salts. Aqueous solutions of (Au-Gn(CO(2)Na)) exhibited micellar properties. Since these NCDs possess a relatively unpassivated metal core and an organic aryl ether shell with micellar and dendritic properties, they are expected to have important potential applications in catalysis.