This first reported case of angiosarcoma of the superior vena cava demonstrates that surgical excision, reconstruction, and irradiation can lead to disease-free survival at 24 months.
May support multimodality therapy for rare SVC angiosarcoma; leaves open need for prospective data on durability and generalizability.
The first reported case of an angiosarcoma apparently arising from the superior vena cava is presented. The patient, a 20-year-old white man, was treated by surgical excision and reconstruction with dacron grafts from the left and right brachiocephalic veins to the right atrium. This was followed by a course of mediastinal irradiation. The patient remained clinically disease-free at 24 months post-treatment. The patient had occasional occupational exposure to polyvinyl chloride.
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Abratt et al. (1983) studied this question.
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