What question did this study set out to answer?

To compare the diagnostic efficacy of spin-echo and gradient-echo magnetic resonance imaging in detecting and excluding chronic left ventricular thrombi.

January 1, 1992Radiology

Left ventricular thrombi: evaluation with spin-echo and gradient-echo MR imaging.

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Why the study?

Does gradient-echo MR imaging improve the detection of left ventricular thrombi compared to spin-echo MR imaging in patients with chronic LV thrombi?

Key Points

To compare the diagnostic efficacy of spin-echo and gradient-echo magnetic resonance imaging in detecting and excluding chronic left ventricular thrombi.
Evaluated 31 patients with suspected chronic left ventricular thrombi using spin-echo (SE) and gradient-echo (GRE) MR imaging.
Blinded review of images was performed independently by three observers against surgical or corroborative diagnostic standards (18 confirmed thrombi, 13 thrombi excluded).
GRE imaging unequivocally detected 16 of 18 confirmed thrombi (with 2 probable and 0 false-negatives), whereas SE imaging detected 12 of 18 unequivocally (5 probable and 1 false-negative).
For thrombus exclusion across 13 cases, SE imaging was unequivocal in 9 and probable in 4, while GRE imaging was unequivocal in 10, probable in 2, and produced 1 false-positive.
GRE imaging achieved superior differentiation of thrombi from adjacent myocardium and the blood pool compared to SE imaging.

Structured PICO

Does gradient-echo MR imaging improve the detection of left ventricular thrombi compared to spin-echo MR imaging in patients with chronic LV thrombi?

Population

31 patients with chronic left ventricular (LV) thrombi

Intervention

Gradient-echo (GRE) magnetic resonance (MR) imaging

Comparator

Spin-echo (SE) magnetic resonance (MR) imaging

Outcome

Detection and exclusion of left ventricular thrombi compared to corroborative diagnostic techniques or surgerysurrogate

Gradient-echo MR imaging provides superior diagnostic accuracy for detecting left ventricular thrombi compared to spin-echo MR imaging by improving differentiation of thrombi from the blood pool and myocardium.

Discussion

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Implication

GRE may improve LV thrombus detection over SE MRI; leaves open need for outcome validation before practice change.

Cite This Study

Jungehülsing et al. (1992) studied this question.

synapsesocial.com/papers/6a89cd281fb56efa37d4720d https://doi.org/10.1148/radiology.182.1.1727287

View Full Paper

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Left ventricular thrombi: evaluation with spin-echo and gradient-echo MR imaging.

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Left ventricular thrombi: evaluation with spin-echo and gradient-echo MR imaging.

Key Points

Structured PICO

Discussion

Implication

Cite This Study

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Also Consider