A new amino acid antibiotic, amiclenomycin is produced by Streptomyces lavendulae subsp. amiclenomycini OKAMI. The chemical structure of amiclenomycin is L-2-amino-4-(4'-amino-2', 5'-cyclohexadienyl)-butyric acid. The antibiotic inhibits growth of mycobacteria and this activity is reversed by biotin and desthiobiotin. α-Methyl-desthiobiotin is coproduced along with amiclenomycin.
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Okami et al. (1974) studied this question.
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