Evaluation of: Gobin AM, Lee MH, Halas NJ, James WD, Drezek RA, West JL: Near-infrared resonant nanoshells for combined optical imaging and photothermal cancer therapy. Nano Lett. 7, 1929–1934 (2007) [1]. Although hyperthermia has been a promising method of cancer treatment for decades, traditional means of heating tissues involve invasive catheters or whole-body heating systems. The use of nanoparticles in hyperthermia therapy has been developed over the last 4 years and involves the near-infrared heating of these nanoshells without harming healthy tissues. The paper under evaluation demonstrates the improved optical imaging of tumors with nanoshells and the improved long-term survival of mice treated with these particles and near-infrared irradiation. The implications of this work and important future steps are explored in this evaluation.
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Hauck et al. (2007) studied this question.
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