(Concluded)Gastrointestinal DisordersAlthough it has been known for some time that the gastrointestinal tract contains the largest proportion of body serotonin, clinical studies relating to this fact have been rather belated.68 It is of interest that peptic ulcer has been noted to be unusually frequent in patients with the carcinoid syndrome.69 However, noncarcinoid persons with peptic ulcer, as well as those with achlorhydria,70 have been found to have normal 5-hydroxyindole-acetic acid values. Two so-called "ulcerogenic tumors" of the pancreas have been analyzed for serotonin in this laboratory, with negative results. To the present, serotonin is merely another addition to . . .
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Albert Sjoerdsma (1959) studied this question.
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